The Ohr-O’Keefe Museum of Art is located on a four acre campus in Biloxi, Mississippi. Set within a grove of ancient Live Oak trees, Frank Gehry designed the Ohr-O’Keefe project as a series of six small pavilions woven among the trees and connected by an open brick plaza. The entire project utilizes an auger-cast concrete pile foundation system intended to minimize impact on the Live Oak trees with the layout of piling based on the existing root system. The primary structural support system for the various buildings utilized structural steel shapes and cast in place concrete on composite metal decking. Primary and secondary framing members were bent, curved, and folded to conform to the complex geometric forms that are fundamental to a Frank Gehry designed project. State of the art computer software (STAAD) was used to analyze and design the structures, and RHINO and AutoCAD were used to produce the detailed 3D computer models and 2D plans, respectively, that made up the construction documents. A wind tunnel study was performed to determine wind design criteria due to the complicated architecture which fell outside the normal bounds of the applicable building codes. The 25,000 square foot Ohr-O’Keefe Museum campus provides facilities for art exhibition and education, and cultural and community events.